Hand of Purity is getting some changes for 5.4, which will will help negate some of the changes that were hotfixed back in March during Throne of Thunder progression.
Hand of Purity
now reduces damage taken from harmful periodic effects by 80% (up from 70%) and reduces damage taken from harmful periodic effects that cannot be prevented by immunities by 40% (up from 0%).
You may remember that Hand of Purity was used for Frostbite on Council of Elders, and made it so easy during the first few weeks of heroic kills that it was necessary to stack pallies for that reason specifically.
This is a nice buff to give it more utility that was taken away with the hotfix.